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十年救治ARDS病人的回顾性分析

目的:研究ARDS的发病率、发病原因、临床生理特征、治疗进展、病死率及其预测因子。设计:回顾性分析。机构:一所教学医院中心ICU。病人:1994年4月~2003年12月期间所有符合AECC标准的ARDS病人。干预:无。方法:对第二军医大学附属长海医院中心ICU在1994年4月~2003年12月间收治的5314例病人中行回顾性分析。符合ARDS诊断的131例病人,其中115例存活时间超过24小时。70.4%的病人为男性,平均年龄为58.2岁。根据入室时间,以2000年1月1日为界将病人分为两组。所有病人在ARDS发生时进行APACHE III 评分、MODS评分和LIS评分。其它采集的指标包括年龄、性别、ICU滞留时间、机械通气时间、气管切开与否、呼吸机相关参数、是否手术以及是否急诊手术。结果:主要致病因素为肺部感染(34.7%)和脓毒症(33.0%),其它为(32.3%)。在入室时,死亡组的MODS评分显著高于生存组,BE值也显  (本文共60页) 本文目录 | 阅读全文>>

《World Journal of Gastroenterology》2014年19期
World Journal of Gastroenterology

Changes in intestinal microflora in rats with acute respiratory distress syndrome

INTRODUCTIONAcute respiratory distress syndrome(ARDS)is a continu-ous pathological process,with acute lung injury(ALI)atits early stage.According to Ashbaugh et al[1],ARDS ischaracterized by alveolar epithelial and endothelial bar-rier disruption,significant inflammation,gas exchangedysfunction and severe respiratory failure.Despite re-markable progress in the pathophysiology and standardtreatment(i.e.,supportive mec...  (本文共10页) 阅读全文>>

《Acta Pharmacologica Sinica》2003年12期
Acta Pharmacologica Sinica

Treatment of acute respiratory distress syndrome

Acute resPiratory distress syndrome(ARDS)15characterized by significant intraPulmonary mismatehof ventilation and Perfusion with inereased right一to一leftshunting,decreased lung eomPlianee,and aeute Pul-monary hyPertension.Pulmonary artery hyPertensioninduees an inerease in Pulmonary mierovaseular filtra-tion Pressure,thereby intensifying Pulmonary Perme-ability edema and right ventrieular dysfunction.Currently,it 15 b...  (本文共2页) 阅读全文>>

《Acta Pharmacologica Sinica》2003年12期
Acta Pharmacologica Sinica

Incidence, prevalence and outcome of adult respiratory distress syndrome: A 12-month prospective multicenter survey in Shanghai

F(),and APACHE 1115 at study entry had no·Or nlar-glnal imPaet on death Predletion,the in一hosPital mortal-ity for Patients with LIS2.5 was 614叹(z,二44).Weeonelude that there 15 ah一gh morbidity and xnortality ofARDS in surVeyed hosPitals in Shanghai,and eurl℃ntresPiratory and intensive eare for ARDS and those atrisk of ARDS should be reassessed,and effeetlve thera-Peutie interventions be imPlemented to reduce themortal...  (本文共1页) 阅读全文>>

《World Journal of Respirology》2015年02期
World Journal of Respirology

Causes of failure in acute respiratory distress syndrome modeling and treatment in animal research and new approaches

INTRODUCTIONAcute respiratory distress syndrome(ARDS)was firstdescribed in 1967[1],and its description was developedinto the Berlin definition in 2011[2].In the clinical studycohort of the Berlin definition,the mortality rate was27%for mild,32%for moderate and 45%for severeARDS[3].Although worsening oxygenation is a riskfactor for ARDS mortality,patients generally die frommultisystem organ failure or a progressive un...  (本文共4页) 阅读全文>>

《Chinese Journal of Traumatology》2007年04期
Chinese Journal of Traumatology

Retrospective analysis on acute respiratory distress syndrome in ICU

})《,u t 40 year、ag(),the(·lini(·al presentati()一(,f a。·t月tor。·、I〕i,·a一《,侧.11、tre、s、yn‘In,me(ARDS)was rer一()rte(11)yA,hl,augh et al’fr()ma、erie、()f l)atie:一t、wi*h rhea(ute.)nset一)f ta(lhyPnea,hypoxelllia,(l(、(·rease《11、ul一n(、一飞a侧(、、、,nplian、·e,and diffusel}ilateral ir一fl ltrati一r一、()na(·hesl ra(11()只rar)h.Despite aolvanees in (一1 ti(·al(·are,the‘leath rate(一f ARDS has remaine(l h 19}1(5()%),wit卜,rol(,nt rel〕o:ts sugge...  (本文共6页) 阅读全文>>